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1996, to start with mesoscopic charge density waves units; and initial electrical measurements on one metallic nanocluster among nanoelectrodes
Multicolor imaging with the bacterial nucleoid and cell division proteins with blue, orange, and in close proximity to-infrared fluorescent proteins
2007, very first authentic-time detection of strand exchange in homologous recombination by RecA; discovery of a lower persistence duration of ends of microtubules; and settled the system of biosensing with carbon nanotubes
This yielded a breakthrough. Within just only a few months, we ended up in a position to evaluate transport by way of an individual solitary-walled carbon nanotube. Based on lower-temperature experiments by a brilliant PhD college student in my team, Sander Tans (now a valued colleague and professor at Delft University of Know-how with the Energetic research lab at AMOLF in Amsterdam), we showed that carbon nanotubes were real quantum wires with pretty extended (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic behaviour.
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of only one wire bridging two electrodes
You're a Christian. If you may make this kind of synthetic mobile, would you be a single step nearer to God, or would the role of God have diminished rather once more?
Atomic drive microscopy shows that vaccinia topoisomerase IB generates filaments on DNA in the cooperative manner
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But carbon nanotubes have remained a study matter of substantial fascination to many. Indeed, the outlook on applying carbon nanotubes to create useful gadgets, in parts for instance radio-frequency electronics, digital electronics and versatile electronics, continues to be shiny.
‘The concept You can find such a factor like a starting, a giant bang, is now a fascinating signpost to contemplate that there was a creator. But far more commonly, and on The premise of pure rationality, I also get there in a Christian interpretation of fact. An atheistic worldview is usually a naturalistic worldview: essentially, there are only atoms and all-natural forces that we are able to measure.
‘That problems the synthetic cell, as Component of the Dutch BaSyC initiative. Craig Venter looked best-down in Those people days and recognized about 5 hundred genes that are minimally essential for just a functioning cell. We want to glance base-up: how do we transfer from the couple molecules to a complete biological technique?
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of a single wire bridging two electrodes
Solid-point out nanopores have tested to generally be a shockingly multipurpose probe for one-molecule Investigation of DNA. I'll describe a few of our recent findings – specifically DNA knots – and our endeavours to develop the abilities of sound-state nanopores even further, in the way of solitary-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.